Sustained effect of spinal cord stimulation on pain and quality of life in painful diabetic peripheral neuropathy.
نویسندگان
چکیده
References 1 Alper KR, Lotsof HS, Frenken GMN, et al. Treatment of acute opiod withdrawal with ibogaine. Am J Addict 1999; 8: 234–42 2 Mash DC, Kovera CA, Pablo J, et al. Ibogaine: complex pharmacokinetics, concerns for safety and preliminary efficacy measures. Ann N Y Acad Sci 2000; 914: 394–401 3 Hoelen DWM, Spiering W, Valk GD. Long QT syndrome induced by the antiaddiction drug ibogaine. N Engl J Med 2009; 360: 308–9 4 BBC News Magazine, April 2012. Available at http://www.bbc.co. uk/news/magazine-17666589
منابع مشابه
Effect of 6 weeks aerobic training on peripheral neuropathic pain and expression of NOTCH1 pathway genes in posterior spinal cord of diabetic male rats
ntrodution: Neuropathic pain is one of the most important factors affecting the quality of life of people with diabetes mellitus; regular exercises may have a role in reducing the pain associated with diabetes. The purpose of this study was the effect of six weeks aerobic training on environmental neuropathic pain and expression of the NOTCH1 pathway in the spinal cord of diabetic male rats. M...
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Spinal cord stimulation (SCS) has been demonstrated to serve as a successful second-line treatment modality for painful diabetic peripheral neuropathy (PDPN), as documented in two randomized clinical trials (RCTs) (1,2). Besides the fact that these two RCTs demonstrate a pain-relieving effect for a period of 6 months after the start of SCS treatment, only small observational studies suggest a l...
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Painful diabetic neuropathy (PDN) is a peripheral neuropathic pain condition that is often difficult to relieve. Spinal cord stimulation (SCS) is a proven effective therapy for various types of mixed neuropathic conditions, yet effectiveness of SCS treatment for PDN is not well established. To our knowledge, ours is the first multicentre randomized controlled trial investigating the effectivene...
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A substantial body of literature is available on the natural history of diabetes, but much less is understood of the natural history of painful diabetic peripheral neuropathy (PDPN), a pervasive and costly complication of diabetes mellitus. Multiple mechanisms have been proposed, including polyol pathway activation, advanced glycosylation end-product formation, and vasculopathic changes. Nevert...
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Objective(s):Painful diabetic neuropathy is associated with hyperexcitability and hyperactivity of spinal cord neurons. However, its underlying pathophysiological mechanisms have not been fully clarified. Induction of excitatory/inhibitory neurotransmission imbalance at the spinal cord seems to account for the abnormal neuronal activity in diabetes. Protective properties of neurosteroids have b...
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ورودعنوان ژورنال:
- British journal of anaesthesia
دوره 111 6 شماره
صفحات -
تاریخ انتشار 2013